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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAN3
All Species:
35.76
Human Site:
T643
Identified Species:
52.44
UniProt:
Q58A45
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58A45
NP_787050.4
741
82181
T643
R
L
L
A
K
L
G
T
I
N
E
R
P
E
F
Chimpanzee
Pan troglodytes
XP_001136622
741
82148
T643
R
L
L
A
K
L
G
T
I
N
E
R
P
E
F
Rhesus Macaque
Macaca mulatta
XP_001097210
741
82134
T643
R
L
L
A
K
L
G
T
I
N
E
R
P
E
F
Dog
Lupus familis
XP_543150
987
105833
T889
R
L
L
A
K
L
G
T
I
N
E
R
P
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q640Q5
691
76362
K598
N
E
R
P
E
F
Q
K
D
P
T
W
S
E
T
Rat
Rattus norvegicus
XP_002724835
883
95283
T785
R
L
L
A
K
L
G
T
I
N
E
R
P
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519591
717
78728
T619
R
L
L
A
K
L
G
T
I
N
E
R
P
E
F
Chicken
Gallus gallus
XP_417120
757
83269
T659
R
L
L
A
K
L
G
T
I
N
E
R
P
E
F
Frog
Xenopus laevis
NP_001128699
631
68072
L538
R
T
I
H
T
A
G
L
A
C
R
V
M
D
P
Zebra Danio
Brachydanio rerio
XP_002666687
799
86684
T701
R
L
L
A
K
L
G
T
I
N
E
R
P
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728797
788
85176
S692
R
I
L
V
K
L
N
S
I
N
E
R
P
D
F
Honey Bee
Apis mellifera
XP_623553
607
67474
P514
L
A
T
I
N
E
R
P
E
L
N
M
E
P
T
Nematode Worm
Caenorhab. elegans
P34653
632
71182
E539
N
T
V
L
E
R
V
E
H
G
T
D
D
A
W
Sea Urchin
Strong. purpuratus
XP_796055
760
83393
V657
R
L
L
C
K
L
G
V
M
N
E
R
P
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36102
679
76436
N586
F
R
L
V
N
K
L
N
C
I
F
G
R
I
E
Red Bread Mold
Neurospora crassa
Q7SDP4
656
73993
V563
E
R
G
D
S
C
G
V
H
N
W
S
E
T
G
Conservation
Percent
Protein Identity:
100
99.8
99.7
74.4
N.A.
90.1
82.2
N.A.
80.8
78.3
58.4
68.2
N.A.
38.5
41.8
31.9
49.3
Protein Similarity:
100
100
99.8
74.7
N.A.
90.9
83
N.A.
86
84.1
64
75
N.A.
55.7
59.6
49.5
62.6
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
100
100
13.3
100
N.A.
66.6
0
0
80
P-Site Similarity:
100
100
100
100
N.A.
13.3
100
N.A.
100
100
26.6
100
N.A.
86.6
0
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
45.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
50
0
7
0
0
7
0
0
0
0
7
0
% A
% Cys:
0
0
0
7
0
7
0
0
7
7
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
7
0
0
7
7
13
0
% D
% Glu:
7
7
0
0
13
7
0
7
7
0
63
0
13
63
7
% E
% Phe:
7
0
0
0
0
7
0
0
0
0
7
0
0
0
63
% F
% Gly:
0
0
7
0
0
0
69
0
0
7
0
7
0
0
7
% G
% His:
0
0
0
7
0
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
7
7
7
0
0
0
0
57
7
0
0
0
7
0
% I
% Lys:
0
0
0
0
63
7
0
7
0
0
0
0
0
0
0
% K
% Leu:
7
57
69
7
0
63
7
7
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% M
% Asn:
13
0
0
0
13
0
7
7
0
69
7
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
7
0
7
0
0
63
7
7
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
69
13
7
0
0
7
7
0
0
0
7
63
7
0
0
% R
% Ser:
0
0
0
0
7
0
0
7
0
0
0
7
7
0
0
% S
% Thr:
0
13
7
0
7
0
0
50
0
0
13
0
0
7
13
% T
% Val:
0
0
7
13
0
0
7
13
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _